FGF/FGFR axis
Targeting the FGF/FGFR axis and its co-alteration allies. Uehara Y, Ikeda S, Kim KH, Lim HJ, Adashek JJ, Persha HE, Okamura R, Lee S, Sicklick JK, Kato S, Kurzrock R.
ESMO Open. 2022 Dec;7(6):100647. doi: 10.1016/j.esmoop.2022.100647. Epub 2022 Nov 29.
PMID: 36455506

JAK/STAT and IRS/PI3K signaling
The pivotal role of JAK/STAT and IRS/PI3K signaling pathways in neurodegenerative diseases: Mechanistic approaches to polyphenols and alkaloids. Kooshki L, Zarneshan SN, Fakhri S, Moradi SZ, Echeverria J.
Phytomedicine. 2023 Jan 31;112:154686. doi: 10.1016/j.phymed.2023.154686. Online ahead of print.
PMID: 36804755

JAK inhibition ameliorated experimental autoimmune encephalomyelitis by blocking GM-CSF-driven inflammatory signature of monocytes. Shao S, Chen C, Shi G, Zhou Y, Wei Y, Wu L, Sun L, Zhang T.
Acta Pharm Sin B. 2023 Oct;13(10):4185-4201. doi: 10.1016/j.apsb.2023.07.026. Epub 2023 Jul 31.
PMID: 37799385 Free PMC article.
4.
Klotho inhibits IGF1R/PI3K/AKT signalling pathway and protects the heart from oxidative stress during ischemia/reperfusion injury. Olejnik A, Radajewska A, Krzywonos-Zawadzka A, Bil-Lula I.
Sci Rep. 2023 Nov 20;13(1):20312. doi: 10.1038/s41598-023-47686-5.
PMID: 37985893